Phytochemical Evaluation and Pharmacological Screening of Coccinia grandis

Authors

  • Shivaji Bole PG Department of Biotechnology, The Oxford College of Science, Bangalore, India.
  • C. Kamatchi PG Department of Biotechnology, The Oxford College of Science, Bangalore, India.
  • Neena Aloysious PG Department of Biotechnology, The Oxford College of Science, Bangalore, India.
  • Linsha Lakshmanan PG Department of Biotechnology, The Oxford College of Science, Bangalore, India.

DOI:

https://doi.org/10.9734/bpi/rabs/v1/3692E

Keywords:

Free radical, C. grandis, anti inflammatory, antioxidant activity

Abstract

Coccinia grandis has been used in traditional medicine for treatment of several diseases. The objective of the present study is to investigate phytochemical constituents and pharmacological properties of Coccinia grandis fruit extracts. In vitro antioxidant and anti inflammatory activity of C. grandis fruit extract were performed. Phtyochemical evaluation revealed the presence of alkaloids, carbohydrates, phytosterols, resins, tannins, flavonoids, proteins and diterpenes. The efficiency of antioxidant activity was found in the order methanol>ethanol>petroleum ether>chloroform>n-hexane. For anti inflammatory study, n-hexane and petroleum ether showed the highest inhibitory activity and least was observed in chloroform followed by ethanol and methanol extracts.

Published

2022-03-31

How to Cite

Shivaji Bole, C. Kamatchi, Neena Aloysious, & Linsha Lakshmanan. (2022). Phytochemical Evaluation and Pharmacological Screening of Coccinia grandis. Research Aspects in Biological Science Vol. 1, 81–87. https://doi.org/10.9734/bpi/rabs/v1/3692E

Issue

Research Aspects in Biological Science Vol. 1

Section

Chapters