Desmoplastic Infantile Ganglioglioma: A Case Report and Review of the Literature
Recent Updates in Disease and Health Research Vol. 1,
27 January 2024
,
Page 105-117
https://doi.org/10.9734/bpi/rudhr/v1/2790G
Abstract
Desmoplastic infantile ganglioglioma (DIG) is a rare glioneuronal tumor characterized by prominent collagen-rich stroma, spindle cell glial component, and small ganglion cells (WHO grade I). The tumor is more frequently identified in the supratentorial region of patients aged less than 1 year with clinical features of macrocephaly or seizures. DIGs are solid-cystic tumors with sharp demarcation from the brain and/or attached to the dura and are associated with a favorable prognosis after complete surgical resection. In this article, we report a case of DIG in a 4-year-old girl presenting with headache, absence seizures, and decreased muscle tone. No clinical signs of recurrence were observed during 8 months of follow-up.
- Desmoplastic infantile ganglioglioma
- central nervous system
- childhood brain neoplasm
- pathology
- prognosis