Environmentally Benign Un-Catalyzed Esterification of Alcohols under Solvent-Free Condition Using Acetyl Chloride: An Experimental Investigation

Abstract

A general and practical route for un-catalyzed esterification of alcohols using acetyl chloride is described under solvent free and energy efficient conditions. Nowadays, the reactions under catalyst and solvent-free conditions are considerably safe, nontoxic, environmentally friendly and inexpensive. Excellent yields, wide applicability to various alcohols, mild reaction conditions, short reaction time, ease of operation makes this method economic and environmentally benign. The advantages of methodology, solvent free, catalyst free, energy efficient and environmentally benign conditions, simple work-up procedure and easy and green separation of the formed HCl will lead to this protocol a green technique for practical organic synthesis.