Peripheral Neurocytoma Arising from an Ovarian Mature Cystic Teratoma in a Pediatric Patient: Case Report and Literature Review of Published Cases

Authors

  • Hirzel Alicia South Broward, Memorial Healthcare System, Joe DiMaggio Children’s Hospital, Hollywood, Florida, US.
  • Freire Rochelle Forward Pathology Solutions, Integrated Regional Laboratories, Aventura, Florida, US.
  • Ortiz Domenika Department of Pathology, School of Medicine, University of Miami, Miller, Miami, Florida, US.
  • P. Rojas Claudia South Broward, Memorial Healthcare System, Joe DiMaggio Children’s Hospital, Hollywood, Florida, US.

DOI:

https://doi.org/10.9734/bpi/rdmms/v7/4970C

Keywords:

Mature cystic teratoma, neurocytoma, neurocytoma within teratoma, neuroepithelial tumor

Abstract

A neurocytoma is a neuronally-differentiated low-grade tumor most commonly found in young or middle-aged adults. Peripheral neurocytoma arising within mature cystic ovarian teratoma is an extremely rare clinical entity with only few published reports to date. We present a case of a neurocytoma arising within a mature cystic ovarian teratoma in a 16-year- old female. Microscopic examination identified a mature cystic teratoma in addition to a 0.5cm diameter neuroepithelial tumor with neuronal differentiation. The Ki-67 proliferative index was <1%. Immunohistochemistry was positive for synaptophysin and neurofilament and negative for OLIG2 and glial fibrillary acidic protein. Based on these findings, the mass was classified as neurocytoma arising within a mature cystic teratoma.

Published

2023-03-28

How to Cite

Hirzel Alicia, Freire Rochelle, Ortiz Domenika, & P. Rojas Claudia. (2023). Peripheral Neurocytoma Arising from an Ovarian Mature Cystic Teratoma in a Pediatric Patient: Case Report and Literature Review of Published Cases. Research Developments in Medicine and Medical Science Vol. 7, 105–113. https://doi.org/10.9734/bpi/rdmms/v7/4970C

Issue

Research Developments in Medicine and Medical Science Vol. 7

Section

Chapters