Study on Non-invasive Management of Rhesus Alloimmunization

Authors

  • Nirmala Agarwal Department of Obstetrics and Gynecology, Sant Parmanand Hospital, New Delhi, India.
  • Sweta Balani Department of Obstetrics and Gynecology, Sant Parmanand Hospital, New Delhi, India.
  • Subhash Arya Department of Obstetrics and Gynecology, Sant Parmanand Hospital, New Delhi, India.
  • Ratna Dua Puri Centre of Medical Genetics, Sir Gangaram Hospital, New Delhi, India.

DOI:

https://doi.org/10.9734/bpi/rdmmr/v9/4492F

Keywords:

Rhesus alloimmunization, intravenous immunoglobulin, middle cerebral artery peak systolic velocity

Abstract

Maternal rhesus alloimmunization occurs when a rhesus- negative pregnant women develops antibody response to fetal red cell rhesus antigen. Rhesus alloimmunization causes fetal hemolysis, anemia and hydrops leading to stillbirth, neonatal morbidity or mortality. We describe successful management of two cases of Rh alloimmunization with high anti-D titers, by the ultrasound Doppler measurement of their peak systolic velocity in the middle cerebral artery (PSV-MCA) and multiple maternal administrations of intravenous immunoglobulin (IVIg).

Published

2021-10-29

How to Cite

Nirmala Agarwal, Sweta Balani, Subhash Arya, & Ratna Dua Puri. (2021). Study on Non-invasive Management of Rhesus Alloimmunization. Recent Developments in Medicine and Medical Research Vol. 9, 37–41. https://doi.org/10.9734/bpi/rdmmr/v9/4492F