A Case Report on Management of Oral Submucous Fibrosis with Intralesional Injection of Hyaluronidase and Dexamethasone

Abstract

Oral submucous fibrosis (OSMF) is a more common chronic premalignant disease. It's mostly caused by chewing betel quid. The progressive hyalinization of the submucosa is a distinguishing feature of OSMF. The fact that it affects the entire mucosa contributes to its resistance and progression. It produces a gradual decrease in mouth opening, which might spread to the pharynx. It is a potentially malignant condition that causes connective tissue fibrosis. Although medical treatment is only symptomatic, optimal doses of injection with corticosteroids, hyaluronidase, and local anaesthesia demonstrated a significant reduction in clinical symptoms. The objective here is to research the means of medical therapy as an adjuvant in reducing the stage of OSMF and by then lowers the necessity of the surgical management or to enhance the success of the surgical management. We present a case of OSMF that was treated in a similar manner and yielded better results than either agent used separately. An increase in mouth opening with a decrease in burning sensation was the most significant outcome of the treatment.