Radionuclide Estimation of the Tumors and Compensatory Capacity of the Kidneys

Abstract

Aim: Assess the tumors and compensatory capacity of the kidneys on the basis of determining the volume of functioning kidney tissue according to single-photon emission scintigraphy (SPECT).

Materials and Methods: 65 patients with kidney parenchyma cancers, 32 patients with cysts, and 15 patients with no kidney pathology were included in our study. In addition, we looked into 57 children with a variety of non-cancerous pathologies. The ratio of the volumes of functioning tissue and particular activities between the afflicted and contralateral kidneys, as well as the ratio of the values of the obtained kidney volumes to the appropriate volume for the patient under research, based on his anthropometry data (sex and age), were employed.

Results: According to the findings, the highest compensatory renal reserve occurs when the volume of functioning tissue of the afflicted kidney decreases and the volume of the contralateral kidney increases. The cases are defined as tumours with infiltrating growth if the ratio of the affected kidney volume to the tumour and contralateral is <0.65, and the ratio of their specific activities is <0.75.

Objects are sometimes referred to as tumours without infiltrating growth.

Conclusions: As a result, the proposed integral parameters allow for the evaluation of the kidneys' compensatory potential.The value of the functional volume according to SPECT allows important information about the functioning parenchyma of the kidney in tumours to be obtained. The information used to select indications for conserving surgery.