Determination of Electromagnetic Radiations and Liver Fibrosis Influences the “Lifespan” of Bone Marrow Cells

Abstract

Different exogenous and endogenous factors effect on production speed and direction of cells in bone marrow. Earlier, it was shown, that liver fibrosis effects on the morphotypes of bone marrow cells. In this investigation, the bone marrow cells answer to liver fibrosis and electromagnetic radiation was investigated. The research objects were bone marrow cells` of different age rats. The "lifespan" of lymphocytes obtained from old animals (Wistar rats, 20 months) in the primary culture exceeded that of young animals (3 months). Fibrosis of the liver, which is induced by the administration of copper sulfate and carbon tetrachloride, reduced the "lifespan" of lymphocytes. Electromagnetic radiation (70 kHz 600 V / m) affects the number of cells in the bone marrow and induces apoptosis. A study of the effect of electromagnetic radiation for 4 hours for 1.3 and 5 days showed a U-shaped dependence of the response at the level of bone marrow cells.