Heterocyclic Compounds Containing Bifunctional \(\beta\) -Aminoketone Skeleton

Abstract

The \(\beta\) -aminoketone fragment is seldom found in several drugs, natural products, and bioactive heterocyclic compounds. The development of novel techniques for preparing \(\beta\) -aminoketones using new technologies has been the subject of numerous recent studies. The aim is to produce products with better yields, faster reaction rates, and lower costs. The main focus of this book chapter is to provide the reader with a broad overview on the synthesis of a variety of heterocycles possessing  \(\beta\) -aminoketone skeleton such as piperidines, pyridopyrazinones, quinolizinones, morpholinones, Indoloisoquinolines, isoindolines, pyrazoles, polycyclic quinolinones, pyrrolidinones, imidazolines, indolizines, indolines, benzodiazepines and many others. Several of these heterocycles show encouraging biological activities that could be crucial in small molecule drug discovery efforts.