Stereotypic Sequential Grooming and an Experimental Model of Some Human Psychoneurotic Disorders

Authors

  • Giorgi Andronikashvili I. Beritashvili Center for Experimental Biomedicine, Georgia.
  • Tea Gurashvili I. Beritashvili Center for Experimental Biomedicine, Georgia and Alterbridge University, Tbilisi, Georgia.
  • Tamila Bagashvili I. Beritashvili Center for Experimental Biomedicine, Georgia and Ivane Javakhishvili Tbilisi State University, Georgia.
  • Ketevan Gogeshvili I. Beritashvili Center for Experimental Biomedicine, Georgia.
  • Giorgi Kvernadze I. Beritashvili Center for Experimental Biomedicine, Georgia.
  • Mikheil Okujava I. Beritashvili Center for Experimental Biomedicine, Georgia and Ilia State University, Tbilisi, Georgia.
  • Senera Chipashvili I. Beritashvili Center for Experimental Biomedicine, Georgia.
  • Nino Akhobadze I. Beritashvili Center for Experimental Biomedicine, Georgia.
  • Marina Nikolaishvili Grigpl Robaqidze University, Georgia and Alterbridge University, Tbilisi, Georgia.
  • Malkhaz Makashvili Ilia State University, Tbilisi, Georgia.

DOI:

https://doi.org/10.9734/bpi/pramr/v5/4007C

Keywords:

Grooming, microstructure, translational medicine, clinical medicine, stress

Abstract

Some instinctive patterns of animal behavior, such as the syntactic grooming chain pattern of rodents, have a rather complex and stereotyped serial structure, a syntactic grooming chain is a fixed action pattern that serially connects several grooming movements in 4 predictable phases that follow I syntactic rule. Grooming is an innate behavior that involves many functions. It has a dual nature - it reflects comfort and stress. Auto grooming is highly sensitive to stressors as well as natural and synthetic anxiolytics. Researchers believe that the study of rodent grooming is a good tool for translational neurobiological studies because of aberrant grooming, namely the synt actic chain of grooming. Disruption of its cephalocaudal direction can be used as an experimental model for some human psycho-nervous disorders.

Author Biographies

Tea Gurashvili , I. Beritashvili Center for Experimental Biomedicine, Georgia and Alterbridge University, Tbilisi, Georgia.

 

Tamila Bagashvili, I. Beritashvili Center for Experimental Biomedicine, Georgia and Ivane Javakhishvili Tbilisi State University, Georgia.

 

Mikheil Okujava, I. Beritashvili Center for Experimental Biomedicine, Georgia and Ilia State University, Tbilisi, Georgia.

 

Published

2023-01-10

How to Cite

Giorgi Andronikashvili, Tea Gurashvili, Tamila Bagashvili, Ketevan Gogeshvili, Giorgi Kvernadze, Mikheil Okujava, … Malkhaz Makashvili. (2023). Stereotypic Sequential Grooming and an Experimental Model of Some Human Psychoneurotic Disorders. Perspective of Recent Advances in Medical Research Vol. 5, 54–70. https://doi.org/10.9734/bpi/pramr/v5/4007C

Issue

Perspective of Recent Advances in Medical Research Vol. 5

Section

Chapters