Oxidative Stress in Breast Cancer

Abstract

Breast cancer is the primary malignant neoplasia that kills women globally. Oxidative stress is an emergent risk factor for breast cancer, mostly due to the existence of a relationship between mitochondria-driven oxidative stress and the occurrence of age-related diseases. Many laboratories have focused their efforts in recent years on understanding the significance of oxidative stress generation in breast cancer disease, although understanding of a "cause and consequence" relationship is still lacking. In light of these issues, this review offers a comprehensive collection of information on oxidative stress research in the field of breast cancer, with an emphasis on data derived from human investigations.