Detection of New Five Tri-allelic Patterns at Penta D Locus in Autosomal STRs during Establishment of Genetic Fingerprint Database for the Iraqi Security Forces

Authors

  • Esam Ghazi Mohammed Salih Ministry of Defense, Directorate of Military Medical Affairs, Iraq.
  • Mohammed Ibrahim Nader Institute of Genetic Engineering and Biotechnology for Postgraduate Studies, University of Baghdad, Baghdad, Iraq.
  • Majeed Arsheed Sabbah Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, Iraq.
  • Mohammed Mahdi Al-Zubaidi Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, Iraq.
  • Hanan Khaleel Mahmood Ministry of Health, Medical-legal Directorate, Paternity and Kinship Section, Iraq.
  • Khalifah Mahdi Salih Ministry of Health, Medical-legal Directorate, Paternity and Kinship Section, Iraq.
  • Dhurgham Hameed Hasan Ministry of Health, Medical-legal Directorate, Paternity and Kinship Section, Iraq.

DOI:

https://doi.org/10.9734/bpi/pramr/v3/3949C

Keywords:

Tri-allelic patterns, DNA typing, autosomal, short tandem repeat ( STR ), PowerPlex® fusion system, Iraqi security forces, Iraq

Abstract

In this chapter, we provide new five instances of tri-allelic patterns that were discovered while building a genetic fingerprint database for 354 volunteers in the Iraqi security forces. The PowerPlex® Fusion System had been used to type these individuals using the next 22 autosomal STRs : D3S1358, D1S1656, D2S441, D10S1248, D13S317, Penta E, D16S539, D18S51, D2S1338, CSF1PO, Penta D, TH01, vWA, D21S11, D7S820, D5S818, TPOX, D8S1179, D12S391, D19S433, FGA and D22S1045.

All five tri-allelic patterns were observed at the Penta D locus and had the genotype 9/11/13, 9.4/13/14, 9/10/11, 7/9/11, and 9/10/14 respectively. Each instance belonged to the Type 2 tri-allelic pattern, which has three alleles that are reasonably evenly distributed. Tri-allelic patterns in autosomal STRs occur in 5 cases out of 354 typed people, which represents a frequency of 1.41%.

Published

2023-01-05

How to Cite

Esam Ghazi Mohammed Salih, Mohammed Ibrahim Nader, Majeed Arsheed Sabbah, Mohammed Mahdi Al-Zubaidi, Hanan Khaleel Mahmood, Khalifah Mahdi Salih, & Dhurgham Hameed Hasan. (2023). Detection of New Five Tri-allelic Patterns at Penta D Locus in Autosomal STRs during Establishment of Genetic Fingerprint Database for the Iraqi Security Forces. Perspective of Recent Advances in Medical Research Vol. 3, 108–120. https://doi.org/10.9734/bpi/pramr/v3/3949C

Issue

Perspective of Recent Advances in Medical Research Vol. 3

Section

Chapters