Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications: An Advanced Study

Authors

  • Duanghathai Pasanta Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand.
  • Khin Thandar Htun Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand.
  • Jie Pan Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand and Shandong Provincial Key Laboratory of Animal Resistant Biology, College of Life Sciences, Shandong Normal University, Jinan 250014, China.
  • Suchart Kothan Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand.

DOI:

https://doi.org/10.9734/bpi/nvst/v6/13060D

Keywords:

Magnetic resonance spectroscopy, liver fat, hepatic steatosis, liver fat fraction, 1H-MRS

Abstract

The number of people suffering from fatty liver disease is rising around the world, sparking interest in noninvasive liver fat research. MRS (magnetic resonance spectroscopy) is a powerful tool for directly measuring metabolites in tissue or other areas of interest. MRS has been used to assess liver fat noninvasively in vivo in both research and clinical studies. In comparison to biopsy and other imaging modalities, MRS has shown excellent performance in assessing liver fat with high sensitivity and specificity. Because of these characteristics, MRS is widely used as the gold standard for noninvasive liver steatosis measurement. The goal of this book chapter is to give a quick overview of the MRS principle and its application for assessing liver fat, as well as to summarize the current state of MRS research in comparison to other techniques.

Published

2021-10-02

How to Cite

Duanghathai Pasanta, Khin Thandar Htun, Jie Pan, & Suchart Kothan. (2021). Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications: An Advanced Study. New Visions in Science and Technology Vol. 6, 168–189. https://doi.org/10.9734/bpi/nvst/v6/13060D

Issue

New Visions in Science and Technology Vol. 6

Section

Chapters