A Brief Review on the Type of Donors, Methods and Complications of Hematopoietic Stem Cell Transplant in Children with Thalassemia Major

Abstract

Hematopoietic stem cell transplantation is a curative treatment modality for children with transfusion-dependent Thalassemia. A transplant has been explored extensively in the last 30 years and presently more than 4000 allogeneic transplants have been performed worldwide. This review provides brief information on Pediatric hematopoietic stem cell transplantation in Transfusion-dependent thalassemia with the objective of providing outcome predictions based on modern transplant technologies and some of the known post-transplant complications.