Inflammatory Markers in Critically Ill Patients with Venous Thrombosis: A Cross-Sectional Study in a Tertiary Hospital

Abstract

Objectives: Vein thrombosis is a major public health issue that has a significant human and economic toll on the country. Venous thrombosis is a major cause of morbidity and mortality in hospitalised patients, and it is potentially preventable. Deep vein thrombosis (DVT) has become a more well-known and potentially preventable cause of morbidity and mortality in hospitalised patients over the last decade. The goal of this study was to look at inflammatory markers in venous thrombosis.

Materials and Methods: A cross-sectional study of patients admitted to tertiary hospitals was done. The research looked at 59 occurrences of venous thrombosis that had been confirmed by radiography. For involvement in the study and the conduct of investigations, written informed consent was obtained. The research was carried out between November 2017 and September 2019.

Results: The study group's average age was 43.6 years (SD=16.4), with a range of 20 to 72 years. There were 48 males (81.4%) and 11 females among the 59 patients (18.6 percent). The mean Body mass index of the patients was 24.33 ± 2.84 kg/m₂. Among 59 patients, 48 patients (81.3%) had elevated CRP. 46 patients (77%) had elevated Serum Homocysteine levels (>15 \(\mu\)mol/L). 74.6 percent of the 59 participants had low HDL, 61 percent had high LDL, and 45 percent had high Triglycerides. The total cholesterol level had increased by 40.7 percent. D dimer levels were elevated in 98. 3%.

Conclusion: We find that unprovoked venous thrombosis is a common concern among individuals aged 20 to 29, who are male and have a BMI of more than 25 kg/m₂. Inflammatory markers were found to be considerably higher in patients with venous thrombosis.