An Unusual Case Presentation on Giant Non-Functioning Adrenocortical Carcinoma
New Horizons in Medicine and Medical Research Vol. 1,
9 March 2022
We herein present a case of giant non-functioning adrenocortical carcinoma without any pressure effects which is a rare entity. Adrenocortical carcinoma is a rare tumour with incidence of 1 per million all over the world. Age distribution is bimodal with peaks occurring at 5-20 years and 40-50 years. Tumours greater than 9 cm commonly involve inferior vena cava (IVC) or right side of heart. 80 percent of the carcinomas are functional. We describe a case report of a rare tumour of a non-functioning adrenocortical carcinoma in a 40 year old female having incidence of 0.5/million world over with no extra-adrenal spread at presentation without IVC or right heart involvement in spite of having a large size of 12 cm. Patient underwent successful surgical extirpation with adjuvant radiotherapy with regular follow ups and disease free survival since the surgery. It is imperative to determine hormone levels in symptomatic and asymptomatic patients with adrenal masses. In a functioning or non-functioning tumour, the likelihood of adrenocortical cancer should not be discounted. All solid incidentalomas more than 5 cm in size on computed tomography (CT)/magnetic resonance imaging (MRI) should be surgically removed, with adjuvant therapy considered following histological evaluation.
- Adrenocortical carcinoma
- inferior vena cava