miRNA and Cancer

Authors

  • Susinjan Bhattacharya Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, Noida, Uttar Pradesh, India.

DOI:

https://doi.org/10.9734/bpi/nfmmr/v15/12373D

Keywords:

microRNA, oncomiR, epigenetic modifications, miRNA processing, sequence variations, ceRNA, network, miRNA replacement therapy

Abstract

The microRNAs are small non coding RNA which plays important role in gene regulation. Problems in miRNA biogenesis can lead to translational repression and even cancer. MicroRNAs can either act as oncogenes or as tumour suppressors. There are many factors that regulate the function of microRNAs. A network of oncogene– miRNA– Tumor Suppressor Gene (TSG) affects not only the normal cellular process but also can lead to tumourigenesis. Thus understanding the regulatory factors and the network can help to revisit the discovery process of therapeutic targets in cancer.

Published

2021-09-06

How to Cite

Susinjan Bhattacharya. (2021). miRNA and Cancer. New Frontiers in Medicine and Medical Research Vol. 15, 173–184. https://doi.org/10.9734/bpi/nfmmr/v15/12373D

Issue

New Frontiers in Medicine and Medical Research Vol. 15

Section

Chapters