Design and Evaluation of Acacia concinna and Sapindus mukorossi Coloaded Denture Cleanser Paste: Assessment of Antimicrobial Potential in Pre-used Dentures

Authors

  • Raghwendra Waghmode Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth, Deemed to be University (Formerly, Krishna Institute of Medical sciences Deemed to be University), Karad, Maharashtra, India.
  • Vipul Sansare Department of Pharmaceutics, Dnyandeep College of Pharmacy, Boraj, Khed, Maharashtra, 415709, India.
  • Gaurav Bhave Department of Pharmacognosy, Indira Institute of Pharmacy, Sadavali, Maharashtra, 415804, India.
  • Vaishnavi Nalawade Department of Pharmacognosy, Indira Institute of Pharmacy, Sadavali, Maharashtra, 415804, India.
  • Anuya Babar Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth, Deemed to be University (Formerly, Krishna Institute of Medical sciences Deemed to be University), Karad, Maharashtra, India.
  • Madhuri Desai Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth, Deemed to be University (Formerly, Krishna Institute of Medical sciences Deemed to be University), Karad, Maharashtra, India.
  • Sujit Nagare Department of Pharmaceutics, Dnyandeep College of Pharmacy, Boraj, Khed, Maharashtra, 415709, India.

DOI:

https://doi.org/10.9734/bpi/napr/v9/6279C

Keywords:

Acacia concinna, sapindus mukorossi, denture cleanser, antimicrobial potential, pre-used dentures

Abstract

The present study was started with aim to formulate Acacia concinna and Sapindus mukorossi coloaded denture cleanser paste and evaluation of its effectiveness in pre-used dentures. The denture cleanser paste containing both powders was formulated and evaluated for cleaning potential, foamability and antimicrobial potential against Staphylococcus aureus and Escherichia coli. All batches of formulated paste showed good cleaning potential as revealed from removal of stains induced by permanent markers, highlighter and picric acid on eggshell. In addition to this, paste showed acceptable antibacterial potential against both microbial strains as well as in pre-used dentures. However, in-vivo studies are necessary to predict the effectiveness of formulated paste. Thus, formulated herbal denture cleanser could be viable alternative to commercially available denture cleansers.

Published

2023-09-18

How to Cite

Raghwendra Waghmode, Vipul Sansare, Gaurav Bhave, Vaishnavi Nalawade, Anuya Babar, Madhuri Desai, & Sujit Nagare. (2023). Design and Evaluation of Acacia concinna and Sapindus mukorossi Coloaded Denture Cleanser Paste: Assessment of Antimicrobial Potential in Pre-used Dentures. Novel Aspects on Pharmaceutical Research Vol. 9, 36–49. https://doi.org/10.9734/bpi/napr/v9/6279C

Issue

Novel Aspects on Pharmaceutical Research Vol. 9

Section

Chapters