Screening of Bioactive Secondary Metabolites and Free Radical Scavenging Activity of Mucuna pruriens Seeds

Authors

  • R. Rajesh Phulo Jhano Medical College, Dumka, Jharkhand, India.
  • V. Sreekala Regional Institute of Ayurvedic Research, Gwalior, India.
  • Dhananjay Srikant Kostastane Autonomous State Medical College, Gonda, 271001, India.

DOI:

https://doi.org/10.9734/bpi/napr/v1/18788D

Keywords:

Mucuna pruriens, reactive oxygen species, In vitro antioxidant activity, DPPH assay, natural antioxidants, flavonoids

Abstract

The purpose of this chapter is to identify Mucuna pruriens seed extract's bioactive phytoconstituents and quantify its in vitro antioxidant activity.

Preliminary phytochemical analysis were done for the detection of bioactive constituents using standard procedures and the DPPH (2, 2-diphenyl-1-picrylhydrazyl) test was used to evaluate the In vitro antioxidant activity.

Mucuna pruriens seed extract was subjected to a preliminary phytochemical study, which revealed the presence of major bioactive substances like phenols, flavonoids, tannins, alkaloids, triterpenes, and phytosterols. The maximal DPPH radical scavenging activity of Mucuna pruriens seed extract in an antioxidant experiment was 72.95%, compared to a maximum activity of 93.24% for the standard control at the same dose (0.2 mg/ml). This is a blatant sign of the drug's potent antioxidant properties.

Mucuna pruriens seeds are abundant source of natural antioxidants and showed high DPPH radical scavenging properties and contains important bioactive phytoconstituents. such as phenols, flavonoids, tannins, alkaloids, triterpenes, and phytosterols.

Published

2023-04-19

How to Cite

R. Rajesh, V. Sreekala, & Dhananjay Srikant Kostastane. (2023). Screening of Bioactive Secondary Metabolites and Free Radical Scavenging Activity of Mucuna pruriens Seeds. Novel Aspects on Pharmaceutical Research Vol. 1, 95–104. https://doi.org/10.9734/bpi/napr/v1/18788D