Effect of l-aspartic Acid Addition on Crystal Growth, Structural, Optical and Biological Applications of l-glutamic Acid Crystals

Abstract

In the present studies, we have successfully grown meta stable \(\alpha\) polymorphs of l-glutamic acid single crystal in the presence of l-asparic acid as an additive by using the slow solvent evaporation method. Amino acid compound have played a significant part in the improvement of technologically important materials since these elements are recognized for their structural, optical and physical properties. The selective additive l-aspartic acid is added at different concentrations into the l-glutamic acid aqueous solution and the effect of the additive on l-glutamic acid polymorphs is reviewed. It  makes that at a level of 0.03 g/100 ml concentration, the additive contributes to the crystallization of l-glutamic acid in \(\alpha\)-form. Meta stable \(\alpha\)- L-glutamic acid crystal presence of L-aspartic acid was grown by slow evaporation method applied moderately considerable antibacterial properties against the eight pathogens that were examined and compared. The antibacterial activity effect of grown metastable \(\alpha\)- L-glutamic acid crystal in the presence of L-aspartic at different concentration (0.03 & 0.08 g/ 100 ml) is analyzed in detail. Powder X-ray diffraction study of grown \(\alpha\) crystals belongs to the orthorhombic crystal structure. The UV-Vis spectral studies of \(\alpha\) crystal have a high transparency range in the complete visible region. The percentage of transmittance of grown a crystals is 82.12% respectively. The impact of l-asparic acid on the antimicrobial action of the grown crystals was studied by utilizing the agar diffusion method.