A Recent Study on Anti-microbial Properties of Some Novel Substituted Indazoles

Authors

  • Jaganmohana Rao Saketi Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India and Department of Chemistry, Government Degree College, Palakonda, Andhra Pradesh, India.
  • S. N. Murthy Boddapati Department of Chemistry, Sir C R Reddy College, Eluru, Andhra Pradesh-534007, India.
  • M. Raghuram Department of Botany and Microbiology, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India.
  • Geetha Bhavani Koduri Department of Chemistry, IIIT-RGUKT, Ongole Campus, Andhra Pradesh, India.
  • Haribabu Bollikolla Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India and Department of Chemistry, Andhra Kesari University, Ongole, Andhra Pradesh, India.

DOI:

https://doi.org/10.9734/bpi/nacb/v3/5724B

Keywords:

Indazole, antimicrobial activity, well diffusion

Abstract

A number of indazole derivatives were reported as potent anti-bacterial and antimicrobial agents.  This chapter outlines our efforts to develop synthesized indazole derivatives with powerful antimicrobial activities. A variety of N-methyl-3-aryl indazoles (5a-5j) were examined for their in-vitro antimicrobial effects.  The synthesized compounds were tested for antibacterial activity against four bacterial strains: Xanthomonas campestris, Escherichia coli, Bacillus cereus, Bacillus megaterium, and Candida albicans.  The biological evaluation studies of these indazole derivatives revealed that some of these tested compounds 5a, 5b, 5i and 5j showed excellent inhibitory activity against different tested microbial strains.

Published

2023-06-28

How to Cite

Jaganmohana Rao Saketi, S. N. Murthy Boddapati, M. Raghuram, Geetha Bhavani Koduri, & Haribabu Bollikolla. (2023). A Recent Study on Anti-microbial Properties of Some Novel Substituted Indazoles. Novel Aspects on Chemistry and Biochemistry Vol. 3, 1–12. https://doi.org/10.9734/bpi/nacb/v3/5724B

Issue

Novel Aspects on Chemistry and Biochemistry Vol. 3

Section

Chapters