A Recent Study on Anti-microbial Properties of Some Novel Substituted Indazoles
Novel Aspects on Chemistry and Biochemistry Vol. 3,
28 June 2023
,
Page 1-12
https://doi.org/10.9734/bpi/nacb/v3/5724B
Abstract
A number of indazole derivatives were reported as potent anti-bacterial and antimicrobial agents. This chapter outlines our efforts to develop synthesized indazole derivatives with powerful antimicrobial activities. A variety of N-methyl-3-aryl indazoles (5a-5j) were examined for their in-vitro antimicrobial effects. The synthesized compounds were tested for antibacterial activity against four bacterial strains: Xanthomonas campestris, Escherichia coli, Bacillus cereus, Bacillus megaterium, and Candida albicans. The biological evaluation studies of these indazole derivatives revealed that some of these tested compounds 5a, 5b, 5i and 5j showed excellent inhibitory activity against different tested microbial strains.
- Indazole
- antimicrobial activity
- well diffusion