Diagnostic Dilemma of Post-abortive Patient with Extensive Uterine and Colonic Necrosis Secondary to Clostridium Perfringens: Case Report at Saint Francis Referral Hospital Ifakara Tanzania

Authors

  • Theresia. A. Karuhanga Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania and Department of Surgery, Saint Francis Referral Hospital, P.O.BOX 73 Ifakara Morogoro Tanzania.
  • Rashidi Mayoka Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania and Department of Surgery, Saint Francis Referral Hospital, P.O.BOX 73 Ifakara Morogoro Tanzania.
  • Fassil Tekie Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania and Department of Surgery, Saint Francis Referral Hospital, P.O.BOX 73 Ifakara Morogoro Tanzania.
  • Tariq S. Muhamed Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania.
  • Yeremia N. Elia Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania.
  • Isabella Masenga Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania and Department of Surgery, Saint Francis Referral Hospital, P.O.BOX 73 Ifakara Morogoro Tanzania.
  • Madoshi Philbert Department of Microbiology, Faculty of Medicine University College of Health and Sciences, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania.
  • Sadikiel Kaale Department of Biochemistry and Physiology, Faculty of Medicine, Saint Francis University College of Health and Sciences, BI.O.BOX 175, Ifakara Mororgoro Tanzania.

DOI:

https://doi.org/10.9734/bpi/mria/v7/764

Keywords:

Uterine- colonic necrosis, C. perfringens, ascending colon colostomy, erythrophagocytosis, lethal toxins, multiple organ failure

Abstract

Post abortive Uterine-colon necrosis secondary to Clostridium perfringens infection is extremely rare of unknown incidence. The most reported cases include abdominal or uterine perforation due to C. perfringes forming visceral necrosis. It is associated with significant morbidity and mortality. The pathogen produces Lecithinase C which is a phospholipase C and it is believed to be involved in the pathologic effects of C. perfringens. Below we present the post incomplete abortion who presented with acute abdominal conditions of which surgical intervention was performed in addition to broad-spectrum antibiotics. Intra-operatively, there was extensive uterine and colonic necrosis and the patient survived but remained with permanent complications of total hysterectomy and lack of colon.

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Published

2024-06-18

How to Cite

Theresia. A. Karuhanga, Rashidi Mayoka, Fassil Tekie, Tariq S. Muhamed, Yeremia N. Elia, Isabella Masenga, … Sadikiel Kaale. (2024). Diagnostic Dilemma of Post-abortive Patient with Extensive Uterine and Colonic Necrosis Secondary to Clostridium Perfringens: Case Report at Saint Francis Referral Hospital Ifakara Tanzania. Medical Research and Its Applications Vol. 7, 75–84. https://doi.org/10.9734/bpi/mria/v7/764

Issue

Medical Research and Its Applications Vol. 7

Section

Chapters