Naturally Occurring Diterpenes as Anti-Hypertensive Agents: A Review

Authors

  • Ashish P. Shah Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Krima Doshi Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Hussain Fatepurwala Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Feba Gleetus Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Shakshi Shah Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Elizabeth Jacob Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Jay Mukesh Chudasama Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Mit Bhatt Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.
  • Ghanshyam Parmar Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara-391760, Gujarat, India.

DOI:

https://doi.org/10.9734/bpi/mono/978-81-19315-51-2/CH22

Keywords:

Hypertension, diterpenes, natural products, antihypertensive activity

Abstract

The prevalence of cardiovascular disease is widely attributed to hypertension (HTN). Diterpenoids are just one example of the many plant-based compounds that have been studied as potential antihypertensive medicines in recent years. Vasorelaxant effect and inhibition of vascular contractility are shown by a number of naturally occurring diterpenes, including forskolin and sativoside. Because of their hypotensive effects, diterpenes have been studied for possible applications in the treatment of hypertension in humans. Several of the naturally occurring diterpenes and the anti-hypertensive effect they have are discussed in this chapter. Also importance of diterpenes in the treatment of hypertension is discussed.

Published

2023-06-24

How to Cite

Ashish P. Shah, Krima Doshi, Hussain Fatepurwala, Feba Gleetus, Shakshi Shah, Elizabeth Jacob, … Ghanshyam Parmar. (2023). Naturally Occurring Diterpenes as Anti-Hypertensive Agents: A Review. Multidisciplinary Approaches in Pharmaceutical Sciences, 201–213. https://doi.org/10.9734/bpi/mono/978-81-19315-51-2/CH22