Microsponge: A Targeted Drug Delivery and Its Applications

Abstract

Despite the need for an unique delivery mechanism that offers delayed and regulated medication release, minimal systemic drug absorption, and diminished side effects, significant systemic and cutaneous side effects. A medication delivery device called a microsponge has the adaptability to load a variety of active chemicals, enabling the regulated release of those compounds to lessen systemic exposure and negative effects. Microsponges are polymeric sponges with a non-flexible structure and a porous surface made of interconnected gaps. The microsponge delivery method offers decreased side effects while extending product stability, improving safety, formulation flexibility, and product efficacy. With its approach, mechanism, programmable release, and characterisation of the microsponge delivery system, this review offers an overview of microsponge technology. Recent information on marketed formulations, their applications, and the list of patents was compiled by review. Additionally, this review includes examples of drug release patterns from microsponges, stability standards, and validation. Although recently employed for oral use, microsponges are routinely used for topical use.