The Indian Sars-Cov-2 Variant: Role in the Reinfection and Immune System Response-Minireview

Authors

  • L. E. Weimer National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
  • G. Cattari Reparto COVID, Ospedale Marino-Alghero, ASSL Sassari, ATS Sardegna, Italy.
  • A. Binelli National Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
  • E. Fanales Belasio Department of Infectious Diseases, DMI, Istituto Superiore di Sanità, Rome, Italy.
  • S. Piras Reparto COVID, Ospedale Marino-Alghero, ASSL Sassari, ATS Sardegna, Italy.
  • A. F. Proddighe SSD Lungodegenza –ASSL Sassari-ATS Sardegna, Italy.
  • F. Sensi Direzione ASSL Sassari, ATS Sardegna, Italy.

Keywords:

Indian variant, evade immunity, reinfection, Sars-Cov-2, survivors

Abstract

Diversification Of Sars-Cov-2 Due To Evolution And Adaptation Processes Has Been Observed Globally And Is Expected.

Most Mutations That Emerge Will Not Provide A Selective Advantage To The Virus. However, Some Mutations Or Combinations Of Mutations May Do So, Such As Increased Transmissibility Through An Increase In Receptor Binding Or The Ability To Evade The Host Immune Response By Altering Surface Structures Recognised By Antibodies. Currently, Four Variants Designated As Variants Of Concern (Vocs) By Ecdc Are Under Surveillance In The Eu/Eea And Around The World (?.1.1.7, ?.1.1.7+E484k, B.1.351 And P.1).

Another Nine Sars-Cov-2 Variants Are Considered Variants Of Interest (Voi) By Ecdc And Additional Variants Are Being Monitoring.

First Reported In India In December 2020, Sars-Cov-2 Lineages B.1.617.1, B.1.617.2 And B.1.617.3 Have Been Increasingly Detected, These Lineages Are Distinct And Differ By Their Characteristic Mutations .The Aim Of This Threat Assessment Brief Is To Assess Potential Public Health Implications Of B.1.617 Variants For Eu/Eea Countries, With A Focus On Lineage B.1.617.2.

Published

2021-07-29

How to Cite

L. E. Weimer, G. Cattari, A. Binelli, E. Fanales Belasio, S. Piras, A. F. Proddighe, & F. Sensi. (2021). The Indian Sars-Cov-2 Variant: Role in the Reinfection and Immune System Response-Minireview. Living With Sars-Cov-2 Variants. An Update in the Pandemic Era, 6–10. Retrieved from https://stm.bookpi.org/LSCVUPE/article/view/2717

Issue

Living with Sars-Cov-2 Variants. An Update in the Pandemic Era

Section

Contents