Advanced Strategies for Unnatural Amino Acid Synthesis and their Applications in Chemistry and Biotechnology

Authors

  • Anija Mol T Philip Department of Chemistry, Hislop College, Nagpur 440001, Maharashtra, India.
  • Shoeb R Khan Department of Chemistry, Hislop College, Nagpur 440001, Maharashtra, India.
  • Mayur V. Khedkar Department of Chemistry, Hislop College, Nagpur 440001, Maharashtra, India.
  • Shibin Chacko Department of Chemistry, Hislop College, Nagpur 440001, Maharashtra, India.

DOI:

https://doi.org/10.9734/bpi/mono/978-93-48006-49-3/CH2

Keywords:

Unnatural Amino Acids (UAA), peptides, proteins, bioconjugation, aldehydes, inhibitors, fluorescent amino acids

Abstract

Unnatural Amino Acids (UAA) are key structural units of various natural products, bioactive molecules, and drugs. Chiral pool, asymmetric synthesis, and racemic synthesis were explored in the synthesis of UAA. UAA plays a very important role in bioconjugation, organocatalysis, labelling of bacterial cells, etc. UAA is used in bioconjugation for attaching fluorophore and small molecules for labelling and drug delivery. Here in this chapter, we discuss the recent synthesis of unnatural amino acids and their applications in total synthesis and biological studies.

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Published

2024-08-13

How to Cite

Anija Mol T Philip, Shoeb R Khan, Mayur V. Khedkar, & Shibin Chacko. (2024). Advanced Strategies for Unnatural Amino Acid Synthesis and their Applications in Chemistry and Biotechnology. Innovations in Science and Technology: Shaping a Sustainable Future (Vol. 2), 9–23. https://doi.org/10.9734/bpi/mono/978-93-48006-49-3/CH2

Issue

Innovations in Science and Technology: Shaping a Sustainable Future (Vol. 2)

Section

Contents