Association of High-sensitivity C-Reactive Protein Level with Central Obesity of the Children: A Case Study in a Tertiary Care Hospital of Bangladesh

Abstract

Background: Obesity is an exaggeration of everyday adiposity. Central weight problems in children has multiplied than standard adiposity now a days, which isn't robotically measured in medical practice. Adipose tissue contributes to the secretion of some of inflammatory cytokines which stimulate the manufacturing of high-touchy C-reactive protein (hs–CRP) via way of means of the liver. The take a look at changed into finished to look the affiliation of hs–CRP degree with crucial weight problems in Bangladeshi children.

Methods: A total of 110 obese children aged between 10 to 18 years with BMI \(\ge\) 95th centile and age and sex matched 55 non-obese children with BMI \(\ge\) 5th to < 85th centile according to Centers for Disease Control and Prevention (CDC) growth chart were selected. A structured questionnaire was prepared taking into account demographic and clinical parameters. The hs-CRP were estimated in study subjects and then correlated to central obesity by waist height ratio (WHtR).

Results: The prevalence central obesity was 45.5% by WHtR and raised hs-CRP levels was 46.4% in obese children. About 62% of obese children had central obesity who had raised hs-CRP level \(\ge\) 2 mg/L (high risk), which showed significant positive correlation with WHtR and was significantly raised in obese children.

Conclusions: A high proportion of central obesity was observed in obese children who had raised hs-CRP level, suggesting that it might be useful to assess future metabolic and cardiovascular complication.