Impact of Microarray on Supernumerary Marker Chromosome and Global Developmental Delay
Highlights on Medicine and Medical Research Vol. 14,
5 June 2021
,
Page 56-62
https://doi.org/10.9734/bpi/hmmr/v14/9390D
Abstract
Small supernumerary marker chromosomes (sSMCs) are structurally abnormal chromosomes that are equal in size or smaller than chromosome 20 and it can be recognised or characterised by conventional karyotype analysis. The molecular characterisation of sSMCs derived from chromosome 15 in prenatal diagnosis in a 38-year-old female is presented in this paper. A combination of a detailed ultrasound examination and karyotype analysis, can provide more precise and rapid prenatal diagnosis of sSMCs.
Keywords:
- Array CGH
- global developmental delay
- Karyotype
- marker chromosome
How to Cite
Bachani, S. ., Dadhwal, V. ., & Deka, D. . (2021). Impact of Microarray on Supernumerary Marker Chromosome and Global Developmental Delay. Highlights on Medicine and Medical Research Vol. 14, 56–62. https://doi.org/10.9734/bpi/hmmr/v14/9390D