Impact of Microarray on Supernumerary Marker Chromosome and Global Developmental Delay

Authors

  • Sumitra Bachani Department of Obstetrics & Gynecology, Vardhman Mahavir Medical College & Safdarjung Hospital, India.
  • Vatsla Dadhwal Department of Obstetrics & Gynecology, All India Institute of Medical Sciences, New Delhi, India.
  • Deepika Deka Department of Obstetrics & Gynecology, All India Institute of Medical Sciences, New Delhi, India.

DOI:

https://doi.org/10.9734/bpi/hmmr/v14/9390D

Keywords:

Array CGH, global developmental delay, Karyotype, marker chromosome

Abstract

Small supernumerary marker chromosomes (sSMCs) are structurally abnormal chromosomes that are equal in size or smaller than chromosome 20 and it can be recognised or characterised by conventional karyotype analysis. The molecular characterisation of sSMCs derived from chromosome 15 in prenatal diagnosis in a 38-year-old female is presented in this paper. A combination of a detailed ultrasound examination and karyotype analysis, can provide more precise and rapid prenatal diagnosis of sSMCs.

Published

2021-06-05

How to Cite

Sumitra Bachani, Vatsla Dadhwal, & Deepika Deka. (2021). Impact of Microarray on Supernumerary Marker Chromosome and Global Developmental Delay. Highlights on Medicine and Medical Research Vol. 14, 56–62. https://doi.org/10.9734/bpi/hmmr/v14/9390D

Issue

Highlights on Medicine and Medical Research Vol. 14

Section

Chapters