Authors
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Bihui Liu
Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing, China and Chongqing Engineering Research Center of Functional Food, Chongqing University of Education, Chongqing, China and Chongqing Engineering Laboratory for Research and Development of Functional Food, Chongqing University of Education, Chongqing, China and College of Biological and Chemical Engineering, Chongqing University of Education, Chongqing, China.
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Xiao Xiao
Department of Gastroenterology, Emergency Medical Center of Chongqing, The Affiliated Central Hospital of Chongqing University, Chongqing, China.
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Xianrong Zhou
Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing, China and College of Food Science, Southwest University, Chongqing, China.
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Jie Zhou
College of Food Science, Southwest University, Chongqing, China.
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Lingxia Lan
College of Food Science, Southwest University, Chongqing, China.
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Xingyao Long
Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing, China and Department of Food Science and Biotechnology, Cha University, Seongnam, Korea.
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Yanni Pan
Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing, China and Department of Food Science and Biotechnology, Cha University, Seongnam, Korea.
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Muying Du
College of Food Science, Southwest University, Chongqing, China.
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Xin Zhao
Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing, China and Chongqing Engineering Research Center of Functional Food, Chongqing University of Education, Chongqing, China and Chongqing Engineering Laboratory for Research and Development of Functional Food, Chongqing University of Education, Chongqing, China.
Keywords:
Gene, Lactobacillus plantarum CQPC01, mice, pickled cabbage, soybean isoflavone
Abstract
A newly found strain, Lactobacillus plantarum CQPC01 (LP-CQPC01), was used for soybean milk fermentation, and its effects against constipation were determined. LP-CQPC01-FSM (LP-CQPC01-fermented soybean milk) was found to have six kinds of soybean isoflavones; the isoflavones of LP-CQPC01-FSM were more than those of Lactobacillus bulgaricus-fermented soybean milk (LB-FSM) and unfermented soybean milk (U-FSM). Animal experiment showed that the MTL, Gas, ET, AchE, SP, VIP, and GSH levels in the constipated mice were increased; however, the SS, MPO, NO, and MDA levels in the constipated mice were reduced by soybean milk treatment. Further, LP-CQPC01-FSM increased the mRNA and protein expression of Cu/Zn-SOD, Mn-SOD, CAT, c-Kit, SCF, and GDNF and reduced the expression of TRPV1 and NOS relative to those of the mice with untreated constipation. LP-CQPC01 could be used as a new starter to produce high-quality soybean milk, which might be used as a functional drink.
