Role of Atorvastatin on Endothelial Function in Patients with Dyslipidemia

Authors

  • Iosif Marincu Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq., 300041, Timisoara, Romania, Methodological and Infectious Diseases Research Center, Timisoara, Romania.
  • Iulia Vidican Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq., 300041, Timisoara, Romania, Methodological and Infectious Diseases Research Center, Timisoara, Romania.
  • Bota Adrian Vasile Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq., 300041, Timisoara, Romania, Methodological and Infectious Diseases Research Center, Timisoara, Romania.
  • Germaine Savoiu-Balint “Victor Babes” University of Medicine and Pharmacy Timisoara, Faculty of Pharmacy, Eftimie Murgu Sq., 300041, Timisoara, Romania.

DOI:

https://doi.org/10.9734/bpi/etdhr/v1/15055D

Keywords:

Atorvastatin, total cholesterol, low-density lipoproteins, flow-mediated dilatation, intima -media thickness

Abstract

Background: The prevalence and mortality rates of coronary artery disease have been known to be higher in the last decade.

Objectives: This study presents a correlation between flow-mediated dilatation (FMD), total cholesterol (TC), and low-density lipoproteins (LDL) in patients with dyslipidemia that are not treated with any hypolipemiant medication (DYS-STAT) vs. dyslipidemia patients treated with atorvastatin (DYS+STAT) to assess the effect of atorvastatin on FMD.

Results indicated a higher prevalence of increased LDL and TC values in the DYS-STAT group vs. DYS+STAT group. Also, the decreased values of FMD were found in DYS-STAT group vs. DYS+STAT group.

Conclusion: Our study suggests the improvement of endothelial function in dyslipidemia patients treated with atorvastatin.

Published

2021-12-20

How to Cite

Iosif Marincu, Iulia Vidican, Bota Adrian Vasile, & Germaine Savoiu-Balint. (2021). Role of Atorvastatin on Endothelial Function in Patients with Dyslipidemia. Emerging Trends in Disease and Health Research Vol. 1, 6–12. https://doi.org/10.9734/bpi/etdhr/v1/15055D

Issue

Emerging Trends in Disease and Health Research Vol. 1

Section

Chapters