Indications of EECP and Clinical Studies

Abstract

An abundance of clinical studies has consistently confirmed the efficacy and safety of EECP for the treatment of angina. The Mulita-center Study of Enhanced External Counter Pulsation (MUST-EECP) is the first multi-center, prospective, randomized controlled trial that studied the effect of EECP on stable angina patients. The Research on Enhanced external Counter pulsation therapy in coronary artery disease (RECC) study found that EECP on top of optimal medical therapy improves myocardial ischemia and prognosis in patients with stable angina. In addition, EECP has been shown to induce collateral formation in the coronaries, thus it is expected to be useful for rest enos is prevention in post-PCI patients [4].  Current evidence suggests that EECP on top of standard medical therapy improves quality of life and rehospitalization rates among patients with NYHA grade II to III stable heart failure. The EECP improved exercise tolerance, cardiac function and quality of life, but not maximal oxygen intake at six months of follow-up, subgroup analysis further showed that among patients >65 years of age, maximal oxygen intake was increased after EECP treatment, indicating a greater extent of benefit for the elderly patients [26]. Evidence from clinical trials indicates that EECP improves psychological and psychiatric symptoms, along with social function and work capacity. MUST-EECP showed that EECP improves daily activity, work, body pain, confidence, stamina, social activities, and anxiety and depression among patients with angina [3]. Incidence of neurodegenerative diseases is increasing. EECP therapy, a safe, non-invasive treatment technique was attempted in these diseases [1].