A Review on the Role of Probiotics and Prebiotics in Human Health

Authors

  • Harshkumar N Patel Department of Medicine, GMERS Medical College, Vadnagar, Gujarat, India.
  • Amar C Sajjan Department of Microbiology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, Telangana, India.
  • Sanyuth Reddy Regalla Gitam Institute of Medical Sciences and Research, Rushikonda, Visakhapatnam, Andhra Pradesh, India.
  • Anand Jadhao Department of Physiology, SRMS Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
  • Jitendra Patel Department of Physiology, GMERS Medical College, Vadnagar, Gujarat, India.

DOI:

https://doi.org/10.9734/bpi/dhrd/v7/4812

Keywords:

Probiotics, prebiotics, gut microbiota, immune modulation, gut-brain axis, gastrointestinal health, chronic disease prevention, microbiome therapy

Abstract

Probiotics and prebiotics play a crucial role in maintaining human health by modulating the gut microbiota, enhancing immune function, and preventing various diseases. Probiotics, which are live microorganisms, confer health benefits when administered in adequate amounts, while prebiotics, which are non-digestible dietary fibres, promote the growth of beneficial bacteria in the gut. Their synergistic action has been linked to improved gastrointestinal health, reduced inflammation, enhanced metabolic functions, and potential applications in oral and systemic diseases. Recent advancements in research highlight their role in modulating the gut-brain axis, reducing the risk of chronic diseases, and improving overall well-being. This review explores the mechanisms, clinical applications, and future prospects of probiotics and prebiotics in human health.

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Published

2025-03-27

How to Cite

Harshkumar N Patel, Amar C Sajjan, Sanyuth Reddy Regalla, Anand Jadhao, & Jitendra Patel. (2025). A Review on the Role of Probiotics and Prebiotics in Human Health. Disease and Health: Research Developments Vol. 7, 77–83. https://doi.org/10.9734/bpi/dhrd/v7/4812

Issue

Disease and Health: Research Developments Vol. 7

Section

Chapters