Epoxidation of Olefins, Monocyclic Terpenes, and Alpha Beta Unsaturated Carbonyls Using Flow Reactor Conditions

Abstract

This chapter highlights about epoxidation of Olefins, Monocyclic Terpenes, and Alpha Beta Unsaturated Carbonyls using Flow Reactor Conditions. Industrial semi-batch epoxidation entails extremely stringent safety controls to prevent the buildup of peroxide species in the reactor throughout the reaction process, which might result in mishaps. To avoid the same, we have developed a simple continuous protocol for the epoxidation of olefins, monocyclic terpenes, and chalcones as reactants to convert into epoxy derivatives using a cyanamide-potassium carbonate combo catalytic system. The novel catalytic system can strongly support aids to reduce the accumulation of the peroxide species, and also yielding moderate to high yields of the desired products. All the new epoxy products were well analysed using ¹HNMR and ¹³CNMR spectroscopy. We are exploring to enhance our flow chemistry system for other novel orgnic transformation. The prepared epoxy synthons have proven to be valuable for various biologically active compounds.