Chemical Characterization and Intrinsic Antimicrobial Activity of Croton Blanchetianus Baill Essential Oil

Authors

  • Sidney Gonçalo de Lima Laboratory of Organic Geochemistry, Postgraduate Program in Chemistry, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina - PI, 64049-550, Brazil.
  • Allan Kayk Sales Meneses Laboratory of Organic Geochemistry, Postgraduate Program in Chemistry, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina - PI, 64049-550, Brazil.
  • Marcelo Costa dos Santos Laboratory of Organic Geochemistry, Postgraduate Program in Chemistry, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina - PI, 64049-550, Brazil.
  • Wanessa Sales de Almeida Food and Nutrition Postgraduate Program, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina - PI, 64049-550, Brazil.
  • Humberto Medeiros Barreto Postgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina - PI, 64049-550, Brazil.

DOI:

https://doi.org/10.9734/bpi/ctcb/v6/17320D

Keywords:

Essential oil, Croton blanchetianus, antimicrobial activity, Euphorbiaceae

Abstract

The emergence of bacterial species resistant to antibiotics has signaled the need for new substances that possess antimicrobial activity or act by enhancing the activity of existing drugs. In this scenario, essential oils are an important alternative. The present study aimed to characterize chemically and evaluate the antimicrobial activity of Croton blanchetianus essential oil. The essential oil was obtained by hydrodistillation and analyzed for antimicrobial activity against strains of Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Candida albicans (ATCC 10231), and a strain resistant to multiple antibiotics to Staphylococcus aureus SA-1199B by the microdilution method. GC-MS analysis identified 29 compounds (95.32%). The main constituents were \(\alpha\)-pinene (19.19%), caryophyllene (11.85%) and bicyclogermacrene (10.42%). The antimicrobial activity was observed on strains of Candida albicans at a concentration of 512 \(\mu\)g mL-1 arising as a source of future research for the development of antimicrobial drugs in the treatment of infections caused by this opportunistic fungus.

Published

2022-11-17

How to Cite

Sidney Gonçalo de Lima, Allan Kayk Sales Meneses, Marcelo Costa dos Santos, Wanessa Sales de Almeida, & Humberto Medeiros Barreto. (2022). Chemical Characterization and Intrinsic Antimicrobial Activity of Croton Blanchetianus Baill Essential Oil. Current Topics on Chemistry and Biochemistry Vol. 6, 114–123. https://doi.org/10.9734/bpi/ctcb/v6/17320D

Issue

Current Topics on Chemistry and Biochemistry Vol. 6

Section

Chapters