NGAL: An Upcoming Biomarker of Interest

Authors

  • Khushbu Jasotani Department of Biochemistry, PGIMS, Rohtak, Haryana, India.
  • Kiran Dahiya Department of Biochemistry, PGIMS, Rohtak, Haryana, India.
  • Pragati Singh Department of Biochemistry, PGIMS, Rohtak, Haryana, India.
  • Sushil Kumar Department of Biochemistry, PGIMS, Rohtak, Haryana, India.
  • Keerti Gupta Department of Biochemistry, PGIMS, Rohtak, Haryana, India.

DOI:

https://doi.org/10.9734/bpi/ctcb/v6/3573C

Keywords:

NGAL, lipocalins, biomarker, lipocalin-2, anti bacterial, kidney diseases

Abstract

Members of the lipocalin protein family are typically small secreted proteins. NGAL, or neutrophil gelatinase associated lipocalin, serves many important functions in the body. It has the potential to act as a biomarker for both diagnosis and prognosis for different diseases. In addition to renal diseases, NGAL participates in the pathogenesis of a number of other diseases, such as cardiovascular diseases, inflammatory disorders, cancer, diabetes, etc. In most disorders, its levels have been linked to disease severity. The main properties and functions of NGAL have been discussed in this chapter which will help in establishing its role in early diagnosis, evaluation of the severity, determining prognosis, and improving the management of various diseases.

Published

2022-11-17

How to Cite

Khushbu Jasotani, Kiran Dahiya, Pragati Singh, Sushil Kumar, & Keerti Gupta. (2022). NGAL: An Upcoming Biomarker of Interest. Current Topics on Chemistry and Biochemistry Vol. 6, 38–45. https://doi.org/10.9734/bpi/ctcb/v6/3573C

Issue

Current Topics on Chemistry and Biochemistry Vol. 6

Section

Chapters