Zinc Oxide Doped with Chlorine: Synthesis, Characterization, and \(\alpha\)-Amylase Inhibitors
Current Topics on Chemistry and Biochemistry Vol. 5,
24 September 2022
,
Page 26-39
https://doi.org/10.9734/bpi/ctcb/v5/3803A
Abstract
In the present study, we prepared Zinc Oxide nanoparticles (ZnONPs) and Zinc Oxide nanoparticles doped with Chlorine (Cl: ZnONPs) by chemical solution method from zinc acetate (ZnAc) and oxalic acid (OX. acid). The characterization of ZnONPs and Cl: ZnONPs were determined by FTIR, X-ray, SEM, and TEM. Also, ZnONPs and Cl: ZnONPs \(\alpha\)-amylase inhibitors were determined. The results of SEM indicated that the average particle size of ZnONPs and Cl: ZnONPs are 46.65-74.64 nm. ZnONPs and Cl: ZnONPs TEM images showed a round shape. The compounds b-d and e gave highly significant inhibitory activity against the \(\alpha\)-amylase enzyme and were very close to that of acarbose, thereby, projecting ZnONPs and Cl: ZnONPs as \(\alpha\)-amylase inhibitors.
- Zinc oxide nanoparticles
- zinc oxide nanoparticles doped with chlorine
- crystallinity
- anti-diabetic activity
- \(\alpha\)-amylase inhibitors