Convenient Synthesis of Orixiarine: Pharmacological and Biological Perspectives

Authors

  • T. Suresh Department of Chemistry, Bharathiar University, Coimbatore, India.
  • K. Velmurugan Department of Applied Chemistry, Karunya Institute of Technology and Sciences (Deemed to be University), Karunya Nagar, Coimbatore, India.
  • P. S. Mohan Department of Chemistry, Bharathiar University, Coimbatore, India.
  • R. Nandhakumar Department of Applied Chemistry, Karunya Institute of Technology and Sciences (Deemed to be University), Karunya Nagar, Coimbatore, India.

DOI:

https://doi.org/10.9734/bpi/ctcb/v4/3435A

Keywords:

N-methylaniline, 1-Bromo-3-methyl-2-butanone, orixiarine, total synthesis

Abstract

Quinoline alkaloids are a group of an important class of heterocyclic compounds that has grown in significance due to its high level of pharmacological effectiveness and variety of biological functions. An elegant and total synthesis of the quinoline alkaloid, orixiarine was obtained from N-methylaniline and 1-bromo-3- methyl-2-butanone. This research paves the path for the synthesis of newer orixiarine derivatives for future investigation in a number of prospective biological studies.

Published

2022-07-23

How to Cite

T. Suresh, K. Velmurugan, P. S. Mohan, & R. Nandhakumar. (2022). Convenient Synthesis of Orixiarine: Pharmacological and Biological Perspectives. Current Topics on Chemistry and Biochemistry Vol. 4, 68–73. https://doi.org/10.9734/bpi/ctcb/v4/3435A