Patients with Pancreatic Duct Fluid Culture and Chronic Pancreatitis Undergoing Surgical Intervention and Its Effects on the Course of the Disease after Surgery

Abstract

The goal was to examine the pancreatic duct fluid culture in patients receiving surgical treatment for chronic pancreatitis and its effects on post-operative outcomes. Uncertainty surrounds the part that bacteria play in the chronic pancreatitis development. 35 patients had surgery, of which 17 received a Freys procedure, 13 a longitudinal pancreatico-jejunostomy, and 5 a cystojejunostomy. Duct fluid culture was taken during surgery, examined, and compared to preoperative factors and postoperative results. Twenty individuals obtained successful duct fluid cultures. Klebsiella (8 patients) was the most typical pathogen isolated. Fasting blood glucose level was the only preoperative factor to demonstrate a meaningful correlation. 11 people had wound infections, of whom 10 had positive duct cultures and 9 had the same organism as the positive duct cultures. Patients without and with infectious problems had a median hospital stay of 9 days and 10 days, respectively. Older theories on sterile PD fluid in CP patients may no longer be valid. Up to 60% of the patients in our research had a favorable PD culture. In patients with septic problems, we can shorten their hospital stays by initiating the proper antibiotics. Large center investigations, however, could help us learn more about the significance of this idea and the part that microorganisms play in the pathogenesis of CP.