Synthesis of Acylals from Aromatic Aldehydes and Their Deprotections Catalyzed by Synthetic Phosphates: Practical and Ecological Approach

Authors

  • Fathallaah Bazi Laboratoire de Chimie Analytique et physicochimie des Matériaux, Université Hassan II, Faculté des Sciences Ben M’Sik, Casablanca, Morocco.
  • Bahija Mounir Laboratoire de Chimie Analytique et physicochimie des Matériaux, Université Hassan II, Faculté des Sciences Ben M’Sik, Casablanca, Morocco.
  • Mohammed Hamza Laboratoire de Chimie Analytique et physicochimie des Matériaux, Université Hassan II, Faculté des Sciences Ben M’Sik, Casablanca, Morocco.
  • Said Sebti Laboratoire de Chimie Physique Catalyse et Environnement, Université Hassan II, Faculté des Sciences Ben M’Sik, Casablanca, Morocco.

DOI:

https://doi.org/10.9734/bpi/cpcs/v7/6583D

Keywords:

Synthetic phosphates, clean process, acylals, protection, deprotection

Abstract

An efficient and clean preparation of acylals from aromatic aldehydes in the presence of synthetic phosphates (flourapatite and hydroxyapatite doped with ZnCl2 and ZnBr2) and acetic anhydride was achieved easily in high yields (86% - 97%) at room temperature under solvent-free conditions. Deprotec- tion of the resulting acylals has also been attained by using the same catalysts under microwave irradiation. This method consistently has advantage of ex- cellent yields (82% - 96%) and a short reaction time (3 - 4 min).

Published

2021-02-06

How to Cite

Fathallaah Bazi, Bahija Mounir, Mohammed Hamza, & Said Sebti. (2021). Synthesis of Acylals from Aromatic Aldehydes and Their Deprotections Catalyzed by Synthetic Phosphates: Practical and Ecological Approach. Current Perspectives on Chemical Sciences Vol. 7, 103–114. https://doi.org/10.9734/bpi/cpcs/v7/6583D

Issue

Current Perspectives on Chemical Sciences Vol. 7

Section

Chapters