Determining the Anthelmintic Activity of Lindernia madayiparense against Indian Earthworms

Abstract

The current study sought to determine the anthelmintic activity of Lindernia madayiparense against Indian earthworms, Pheretima posthuma. Helminthiasis poses a serious risk to the public's health and increases the incidence of pneumonia, eosinophilia, anemia, and malnutrition in developing countries. Decoction and continuous hot extraction methods were used to create various extracts. To identify the presence of phytochemical constituents, preliminary qualitative analysis was performed on all L. madayiparanse extracts. The best anthelmintic activity among the studied extracts against earthworms was demonstrated by the ethanol extract, which was also superior to other extracts at all concentrations and closely matched the conventional medication, albendazole. A dose-dependent paralytic effect and timing of death were present in all of the studied extracts. Certain results led to the hypothesis that the existence of these secondary metabolites, such as alkaloids, flavonoids, terpenoids, tannins, and saponins, may be the cause of the observed anthelmintic activity.