Role of Protozoans in Causing Cancer in Human

Authors

  • Mohammad Salim Department of Higher Education, S. G. S. Govt P.G. Autonomous College, Sidhi, Madhya Pradesh, India.
  • Mohammad Shahid Masroor People’s College of Dental Sciences and Research Center, People’s University, Bhopal, Madhya Pradesh, India.
  • Shagufta Parween Department of Human Anatomy, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.

DOI:

https://doi.org/10.9734/bpi/codhr/v10/18016D

Keywords:

Protozoans, cancer in humans, burkitt’s lymphoma, hodgkin lymphoma, brain and breast cancer, gastrointestinal cancer

Abstract

Infections are found as one of the causes of cancer with almost every group of microorganisms involved. Some of these infections developing cancers are continuously being transmitted in society. International Agency for Research on Cancer (IARC) has certified certain microorganisms developing cancer in humans. Protozoans are one of them. They are eukaryotic, unicellular, anthroponotic microorganisms. Protozoans cause cancer in humans via the insertion and integration of their DNA sequences in the host cells stimulating cell division and proliferation by the release of reactive oxygen and nitrogen radicals developing DNA damage and p53 gene inhibition. This review discusses some cancer-causing protozoan parasites like Plasmodium falciparum, Leishmania donovani, Trypanosoma brucie, Toxoplasma gondii, Trichomonas vaginalis, Blastocystis hominis, Theileria microti and Cryptosporidium parvum in the light of recent researches done so far in the field of microbial origin of cancer.

Published

2023-01-30

How to Cite

Mohammad Salim, Mohammad Shahid Masroor, & Shagufta Parween. (2023). Role of Protozoans in Causing Cancer in Human. Current Overview on Disease and Health Research Vol. 10, 79–100. https://doi.org/10.9734/bpi/codhr/v10/18016D