The Scope of Stem Cells in Periodontal Regeneration: A Review

Authors

  • V. Thomas George Department Periodontology, Pushpagiri College of Dental Sciences, Kerala, India.
  • Nebu George Thomas Department of Periodontology, Pushpagiri College of Dental and Sciences, Pushpagiri Research Centre, Pushpagiri College of Medical Sciences, Kerala, India.
  • Saumya John Department Periodontology, Pushpagiri College of Dental Sciences, Kerala, India.
  • Prameetha George Ittycheria Department Periodontology, Pushpagiri College of Dental Sciences, Kerala, India.

DOI:

https://doi.org/10.9734/bpi/cimms/v9/4255E

Keywords:

Mesenchymal stem cells, dental mesenchymal stem cells, periodontal ligament stem cells, cell sheet engineering

Abstract

Chronic periodontitis is an inflammatory disease that destroys the tooth's supporting structures. Periodontal therapy's ultimate goal is to regenerate these destroyed structures. Stem cells are the most recent periodontal regeneration entrant. Dental Mesenchymal Stem Cells (DMSC) are currently the focus of research since they can be extracted with relative simplicity and have a low donor morbidity. As a result, this review has gone through all of the distinct DMSC that are available, the many properties that support their capacity to differentiate into periodontal cells, and the extent to which they have been used in periodontal regeneration. Also, we have drawn attention to various innovations in the use of stem cells for periodontal tissue engineering and the extent of translational research with promising results in periodontal regeneration.

Published

2022-11-18

How to Cite

V. Thomas George, Nebu George Thomas, Saumya John, & Prameetha George Ittycheria. (2022). The Scope of Stem Cells in Periodontal Regeneration: A Review. Current Innovations in Medicine and Medical Science Vol. 9, 70–94. https://doi.org/10.9734/bpi/cimms/v9/4255E