Mitochondrial Dynamics in Triple Negative Breast Cancer

Authors

  • Priyanka Menon Kunnel Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, India.
  • Bibu John Kariyil Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, India.

DOI:

https://doi.org/10.9734/bpi/cimms/v7/3979E

Keywords:

Triple negative breast cancer, mitochondrial dynamics, fusion, fission

Abstract

Triple Negative Breast Cancer (TNBC) is a type of breast cancer with short survival rates. It is an aggressive malignancy with large size. It is also more resistant to chemotherapy & is highly proliferative. They have higher concentration of stem cells & immune cells compared to other breast cancers. A top-notch mitochondrial pool is necessary for these alterations to work. The health of the mitochondria is continuously assessed by mitochondrial dynamics (cycles of fusion and fission). Recent advances in the knowledge of mitochondrial dynamics in TNBC have demonstrated their critical function in the growth and spread of tumours.

Published

2022-11-09

How to Cite

Priyanka Menon Kunnel, & Bibu John Kariyil. (2022). Mitochondrial Dynamics in Triple Negative Breast Cancer. Current Innovations in Medicine and Medical Science Vol. 7, 94–105. https://doi.org/10.9734/bpi/cimms/v7/3979E

Issue

Current Innovations in Medicine and Medical Science Vol. 7

Section

Chapters