Iron Deficiency Anemia Affect Glycated Albumin and Glycated Hemoglobin Levels in Non-diabetic Adults

Authors

  • P. Jyothsna Departments of Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
  • M. M. Suchitra Departments of Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
  • M. Kusuma Kumari Departments of Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
  • C. Chandra Sekhar Departments of Hematology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
  • N. Rukmangadha Departments of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
  • Alok Sachan Departments of Endocrinology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
  • B. Siddhartha Kumar Departments of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

DOI:

https://doi.org/10.9734/bpi/cidhr/v9/6685E

Keywords:

Diabetes mellitus, myelodysplastic disease, glycation, glycated albumin

Abstract

This chapter evaluates about Iron deficiency anemia affect glycated albumin and glycated haemoglobin levels in non-diabetic adults. Iron deficiency anemia (IDA) can increase the red blood cell turnover which can increase glycation of Hb leading to higher HbA1c values as observed in blood loss, hemolysis, hemoglobinopathies, red cell disorders and myelodysplastic disease. The prevalence of diabetes is rapidly rising all over the globe at an alarming rate. A total of 100 subjects attending Medicine and Haematology outpatient department of the Institute were recruited into the study and screened for IDA. Among the subjects screened thirty cases diagnosed with IDA during the period of December 2019 to January 2020 were included into the study. HbA1c is considered an important marker of glycaemic control as it estimates average blood glucose of the previous three months, hence providing a better estimate of average blood glucose than measurement of blood glucose directly. It is imperative to also look for anemia and further into the reasons for the anemia as it is going to be a major confounding factor which can adversely impact the treatment of diabetes mellitus.

Published

2023-12-14

How to Cite

P. Jyothsna, M. M. Suchitra, M. Kusuma Kumari, C. Chandra Sekhar, N. Rukmangadha, Alok Sachan, & B. Siddhartha Kumar. (2023). Iron Deficiency Anemia Affect Glycated Albumin and Glycated Hemoglobin Levels in Non-diabetic Adults. Current Innovations in Disease and Health Research Vol. 9, 1–14. https://doi.org/10.9734/bpi/cidhr/v9/6685E