Role of Anti-Mullerian Hormone as a Predictor of Ovarian Function in Assisted Reproductive Techniques: An Advance Study

Abstract

In order to prepare treatment schedules, prevent OHSS, and advise the couple, it is important to predict ovarian reserve and ART cycle performance.  The aim of this study is to confirm the accuracy of AMH estimation as a predictor of a woman's fertility potential. This is a retrospective study of the effectiveness of multiple IVF/ICSI cycles on 100 women at an infertility centre, using the same protocols and procedures.AMH levels were found to be elevated in 20 people, low in 23 women, and average in 57 women. All women with a normal AMH had a good ovarian response; all women with a moderate AMH had a good ovarian response except one; and all women with a low AMH had a poor ovarian response. 128 cycles of IVF/ICSI were performed on hundred women, 184 embryo transfers were done with fresh and cryopreserved embryos, with clinical pregnancy in 49 women. In 57 women with normal AMH in 76 ART cycles, 123 embryo transfers, 39 clinical pregnancies occurred; in 20 women with high AMH in 28 ART cycles, 44 embryo transfers, 9 had clinical pregnancy; in 23 women with low AMH in 24 ART cycles, 17 embryo transfers, only one became pregnant. AMH can be used as a diagnostic and prognostic marker for ovarian reaction and hyperstimulation in women with PCOS, and the stimulation protocol can be changed to avoid OHSS.