Mass Intake of Hydroxychloroquine or Chloroquine during Covid-19 Pandemic: Possible Consequences in Endemic Malaria Settings
DOI:
https://doi.org/10.9734/bpi/cdhr/v6/7724DKeywords:
Malaria, Covid-19, SARS-Cov-2, chloroquine, hydroxychloroquineAbstract
The world is currently undergoing a new pandemic for which no curative treatment is available. Coronavirus disease 2019 (Covid-19) has spread to 183 countries and killed numerous people. Many reports presented chloroquine (CQ) and hydroxychloroquine (HCQ), former drugs used against malaria, as the best current choice to fight this terrible disease. As these molecules had been withdrawn in malaria treatment policy due to chemoresistance, their reintroduction could have some consequences. Though local malaria prevalence could decrease for a while, molecular changes are likely to happen on some plasmodium falciparum genes involved in conferring drug resistance. If these molecules are widely administered, this could threaten efforts in malaria control.