Determining the Anthelmintic Activity of Extracts of Aerial Parts of Tephrosia spinosa (L.f.) Pers

Authors

  • K. Ilango Department of Pharmaceutical Chemistry, College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur - 603 203, Chengalpattu (Dt), Tamil Nadu, India.
  • R. Xavier Arulappa Department of Pharmaceutical Chemistry, S.A. Raja College of Pharmacy, Vadakankulam – 627 116, Tirunelveli (Dt), Tamil Nadu, India.

DOI:

https://doi.org/10.9734/bpi/caprd/v9/2656C

Keywords:

Tephrosia spinosa, pheretima posthuma, anthelmintic activity

Abstract

Purpose: The objective of this study is to determine the anthelmintic activity of Tephrosia spinosa (L.f.) Pers on Indian earth worms. It is a stiffy thorny shrub, commonly found in south India.

Methods: Chloroform and methanol extracts of T. spinosa were investigated for anthelmintic activity in Indian earth worms (Pheretima posthuma) using albendazole (10 mg/ml) as standard reference and normal saline as control. The times required to paralyses and kill the worms were calculated.

Results: When compared to albendazole, the aerial parts of T. spinosa (L.f.) Pers exhibited significant anthelmintic activity (p<0.001).

Conclusion: It is concluded that Tephrosia spinosa has paralytic effect on Indian earth worms.

Published

2022-02-23

How to Cite

K. Ilango, & R. Xavier Arulappa. (2022). Determining the Anthelmintic Activity of Extracts of Aerial Parts of Tephrosia spinosa (L.f.) Pers. Current Aspects in Pharmaceutical Research and Development Vol. 9, 45–49. https://doi.org/10.9734/bpi/caprd/v9/2656C

Issue

Current Aspects in Pharmaceutical Research and Development Vol. 9

Section

Chapters