Recent Advancements on Callus and Cell Suspension Cultures: An Effectual Reserve for the Production of Pharmaceutically Significant Metabolites

Authors

  • Ashok Ahuja Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.
  • Manoj Kumar Tripathi Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.
  • Sushma Tiwari Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.
  • Niraj Tripathi Directorate of Research Services, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.
  • Gyanendra Tiwari Department of Plant Physiology, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.
  • Nishi Mishra Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.
  • Shashank Bhargav Department of Plant Molecular Biology and Biotechnology, College of Agriculture, Rajmata Vijayraje Scindia Agricultural University, Gwalior 474002, India.
  • Sharad Tiwari Biotechnology Centre, Jawaharlal Nehru Agricultural University, Jabalpur 482004, India.

DOI:

https://doi.org/10.9734/bpi/caprd/v6/2260C

Keywords:

Secondary metabolites, callus culture, cell suspension culture, medicinal plants, metabolic engineering, bioactive, withanolides, bacosides, glychyrhizin, terpenoids, reserpine, plumbagin, indole alkaloids, secoirridoids, xanthones

Abstract

Secondary metabolites of pharmaceutically importance or phytopharmaceuticals comprise alkaloids, glycosides, flavonoids, volatile oils, tannins, resins etc. At present, most of these secondary metabolites are extracted from wild or cultivated plants since their chemical synthesis is either tremendously tough or economically impracticable. Production through callus and cell suspension cultures is a gorgeous substitute, nevertheless till yet this has had only restricted marketable accomplishment owing to less-existence of empathetic of how these metabolites are synthesized. The current book chapter has summarized some of the current progresses and investigations conducted by authors for the production of some of the useful bioactive secondary metabolites viz., withanolides, bacosides, glychyrhizin, reserpine, ajmalicine, amarogentin, plumbagin and terpenoids from callus and cell suspension cultures of corresponding plant species. The similar have been deliberated vastly.

Published

2021-12-06

How to Cite

Ashok Ahuja, Manoj Kumar Tripathi, Sushma Tiwari, Niraj Tripathi, Gyanendra Tiwari, Nishi Mishra, … Sharad Tiwari. (2021). Recent Advancements on Callus and Cell Suspension Cultures: An Effectual Reserve for the Production of Pharmaceutically Significant Metabolites. Current Aspects in Pharmaceutical Research and Development Vol. 6, 96–111. https://doi.org/10.9734/bpi/caprd/v6/2260C