Investigating the Anti-inflammatory Activity of Wheatgrass Juice in Albino Rats

Abstract

To study the anti-inflammatory effect of wheatgrass juice in albino rats. Anti-inflammatory activity of wheatgrass juice was evaluated by using carrageenin-induced rat hind paw edema model for acute study, rexin pellet-induced granuloma in rat model and formalin-induced rat hind paw edema model for chronic study. The results obtained were compared with diclofenac Sodium, standard drug and control. Wheatgrass produced significant anti-inflammatory effect in chronic models. In rexin pellet model, the effect of wheatgrass was more than diclofenac sodium. In formalin-induced rat hind paw edema model, the effect of wheat grass was less than diclofenac sodium. In carrageenin-induced rat hind paw edema model wheatgrass juice showed very minimal activity. However, the wheatgrass juice showed no significant anti-inflammatory activity in acute models. Wheatgrass juice exhibits anti-inflammatory activity in chronic inflammation.