Determination of Anti-Inflammatory Potential of Cassia italica (Mill) Lam. EX. FW. Andrews Leaves

Abstract

Cassia species have been of keen interest in phytochemical and pharmacological research due to their excellent medicinal values.  The methanolic extract of the leaves of Cassia italica was investigated for its anti inflammatory activity in animal models. The extract at different doses used showed good anti inflammatory activity which has been done significantly, by the formation of oedema induced by carrageenan and formalin. These results were also comparable to Indomethacin, the reference drugs used in this study. The results from present study indicate the efficacy of the methanolic extract as a therapeutic agent in acute as well as chronic inflammatory conditions. Thus it could be concluded that Cassia italica leaves extracts possess significant anti-inflammatory properties.

Objective: To investigate the carrageenan and formalin induced paw edema in Cassia italica.